KPV 10mg

Molecular formula:
C194H303N45O59

Molecular weight:
≈ 3758 g/mol

Scientific Description (RUO Only)

KPV is a small tripeptide fragment composed of Lysine, Proline and Valine that is derived from the C-terminal end of α-melanocyte-stimulating hormone (α-MSH), which retains potent anti-inflammatory and epithelial-protective activities while lacking the pigmentation effects of the parent molecule. It acts by engaging melanocortin receptors and modulating key immune signaling pathways such as to reduce the production of pro-inflammatory cytokines like TNF-α, IL-1β and IL-6. KPV has demonstrated efficacy in preclinical models of skin inflammation, gut barrier dysfunction, and epithelial repair, suggesting therapeutic potential in inflammatory bowel disease, dermatoses, and tissue healing. Because of its small size and stability, KPV is being explored for its ability to act as a more targeted, less side-prone alternative to broader anti-inflammatory agents. All information is provided strictly for research and analytical use only.